Agnes Simone Agnes Simone

Estrogen and Mental Health: How Hormones Affect Mood, Anxiety, and Brain Function

Estrogen is both a reproductive hormone and a neuroactive hormone. It crosses the blood-brain barrier, binds to receptors throughout the brain, and regulates the neurotransmitter systems responsible for mood, anxiety, motivation, and cognition. When estrogen levels are stable, these systems function efficiently. When estrogen fluctuates or declines — across the menstrual cycle, postpartum, and during perimenopause — the mental health effects can be profound.

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Agnes Simone Agnes Simone

Postpartum OCD vs Postpartum Anxiety: What New Parents Need to Know

Postpartum OCD and postpartum anxiety are common conditions in new mothers that can look similar but have key differences. Postpartum OCD involves intrusive thoughts and compulsions, while postpartum anxiety presents as more generalized worry. Both are highly treatable with the right support.

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Agnes Simone Agnes Simone

Why ADHD Is Missed in High-Functioning Women

Adult ADHD in women is frequently missed, delayed, or misattributed, especially in those who appear high functioning. Understanding why can be deeply validating and can open the door to more accurate diagnosis and effective treatment.


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Agnes Simone Agnes Simone

Progesterone and the Patterns of Women’s Health

Progesterone is often described as a “reproductive hormone,” but its role in the body goes far beyond fertility and pregnancy. Progesterone affects menstrual cycles, mood, sleep, brain function, and overall well-being, and changes in progesterone levels can have real physical and emotional effects throughout a woman’s life.

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Agnes Simone Agnes Simone

What Postpartum Care Planning With a Psychiatrist Looks Like

Welcoming a new baby is one of the most meaningful transitions in someone’s life, but it is also a time of major physical, emotional, and hormonal change. I never want new parents to enter the postpartum period feeling alone, overwhelmed, or unsure of what to expect. This is why I walk all my expecting moms and dads through a postpartum care plan well before delivery.

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